World number two Mickelson was with Dustin Johnson, with the pair playing Bubba Watson and Jeff Overton.
BBC: Ryder Cup 2010: Seve Ballesteros inspires Europe team
Stewart Cink and Matt Kuchar lead Rory McIlroy and Graeme McDowell while Bubba Watson and Jeff Overton are up on Padraig Harrington and Luke Donald.
BBC: Ryder Cup 2010: US edge rain-affected first day
Other pairings included Masters champion and world number two Phil Mickelson with Rickie Fowler, the youngest player in the US team at 21, Jim Furyk and Jeff Overton, Stewart Cink and Matt Kuchar and Bubba Watson and Dustin Johnson.
BBC: Ryder Cup 2010: Harrington 'best' in Cup practice
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