Other wing options for Wales include Leigh Halfpenny, Tom James, Jamie Roberts, Morgan Stoddart and Richard Fussell.
Kevin Morgan replaces the injured Gareth Thomas at full-back, while James Hook and Jamie Robinson are the centre duo and Dafydd James gets a chance on the wing.
The other players leaving Selhurst Park are Scott Flinders, Carl Fletcher, Ryan Carolan, James Dayton, Jamie Smith and David Wilkinson.
But their methods were unproductive, notably when Williams' replacement Tom James drifted away from Jamie Roberts after fly-half Jones created Wales' best chance of the day.
Bradford pulled clear after the break through Platt, Jamie Langley and James Evans, before Briers' late consolation.
Away with the Wales squad are Bradley Davies, Richie Rees, Tom James, Leigh Halfpenny, Jamie Roberts and Tom Shanklin.
Jamie Roberts, James Hook and Jonathan Davies are now Wales' only fit centres.
Tries from Jamie Roberts and James and two nerveless conversions from Ben Blair completed a remarkable comeback, before a scoreless extra time led to the competition's first shoot-out.
Goalkeeper James had to replaced by Jamie Ashdown in the closing stages before Webber was carried away with a knee problem, leaving Pompey to finish the match with 10 men.
Tony Puletua scored twice for Saints, whose other tries came from joint skipper James Graham, Lee Gaskell and Jamie Foster, who kicked four out of his five attempts at goals.
Since topping the Sound of 2011 list, Jessie J's album Who You Are has gone on to be the biggest-selling debut album of the year in the UK. She was joined in the top five by James Blake, The Vaccines, Jamie Woon and Clare Maguire.
With Davies unable to partner Jamie Roberts in midfield, James Hook was moved to centre, allowing Stephen Jones to regain the fly-half spot he had lost for the 24-6 victory in Scotland.
Henson, who won the last of his 31 Wales caps against Ireland in March 2009, wants to be considered for Welsh selection in a competitive-looking midfield that includes Jamie Roberts, Jonathan Davies and James Hook plus experienced injured duo Andrew Bishop and Tom Shanklin.
The absence of both Murray and Bogdanovic is very likely to mean a place in the singles squad for Scotland's Jamie Baker, plus Dan Evans and James Ward.
As the costs mounted, the trial of Jamie Gray, his wife Julie, son James Junior and daughters Jodie and Cordelia got under way at Bicester Magistrates' Court.
David James and Ledley King have been discarded, while Liverpool stalwart Jamie Carragher has announced his international retirement for the second time.
Five of them will be directed by already selected notables: actress Eva Longoria, actor Jamie Foxx, fashion designer Georgina Chapman, musician James Murphy of LCD Soundsystem and Biz Stone, the co-founder of Twitter.
Gale maintained his 100% record by landing his fifth goal, adding a drop goal five minutes from the end before England hooker James Roby grabbed a last-minute consolation try for Saints, Jamie Foster kicking the conversion.
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After tries for Kirk Yeaman (2) and Tom Briscoe, Jamie Foster pulled one back before second-half efforts from James Roby, Ade Gardner and Tony Puletua.
They doubled their advantage six minutes later when James Graham hit a flat Cunningham pass to twist his way over, Jamie Foster goaling both tries to put Saints in the driving seat.
But James went over for a try, converted by Blair, and fellow winger Jamie Roberts went over the gameline a second time before the break.
He lines up in a reshaped back division that sees James Hook at full-back, Morgan Stoddart on the other wing and fit-again Jamie Roberts forging a midfield partnership with Jonathan Davies.
Leeds had England forward Jamie Jones-Buchanan placed on report for a crunching tackle on Saints front rower James Graham, while St Helens' Leon Pryce was sin-binned for a blatant professional foul.
Smith had rested several players - including Danny McGuire, Leon Pryce, James Graham and James Roby - to give fringe players such as Rob Purdham, Mickey Higham, Paul Sykes and Jamie Jones-Buchanan a chance to impress.
Paul Emerick, Jamie Corsi, Ashley Smith, Phil Dollman, Gareth Maule, Alix Walker, Lewis Evans and James Harris have all signed contract extensions at Rodney Parade.
James Hook passed to full-back Byrne who showed an electric burst of pace to evade an attempted tackle by Jamie Heaslip and score in the corner.
But he was unsettled by some hostile bowling from James Franklin after the interval and was finally out for 65 when a bouncer hit his gloves and went through to Jamie How.
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