By the 1930s, the horses had been replaced by cars with the completion of the aptly named Going-to-the-Sun Road, a heart-in-your-mouth rollercoaster that climbs past cascading waterfalls and gaping cliffs up to the continental divide at 6, 646ft-high Logan Pass.
Bouzigues, just down the road, is the heart of the ostreiculture industry.
Baalbeck, in the Bekaa Valley, is the agricultural heart of Lebanon, and a road-trip there from Beirut leads past the town of Chtaura, where farms produce some of the Middle East's most sought-after dairy products.
Nawab leapt on the kick-starter of his motorcycle, and in one smooth motion flicked on the lights and shot out of the threshing-floor gates, onto the quarter-mile driveway leading from the heart of the farm to the road.
Mr Thubron spent eight months travelling the 11, 300 kilometres (7, 000 miles) of the old Silk Road from Xian in the heart of China to Antioch (Antakya) in Turkey and, although he scrupulously admits in a note that his trip was broken by fighting in northern Afghanistan and that he was obliged to continue the following year, this interruption does not disrupt the flow of his narrative.
The city's fashionable heart is the corner of Oxford Street and Glenmore Road, in Paddington, where some of the most exciting Australian designers are conveniently clustered.
For Democrats, the road to a lasting majority runs through the heart of the middle class.
The Rockwell (181 Cromwell Road) is an independently owned hotel in the heart of Kensington.
The Perseverance Trail begins at the end of Basin Road, about 1.5 miles from the heart of downtown Juneau.
They suggested we delve deeper into the heart of the region and tackle the switchbacks of Drum Canyon Road to visit the Old West town of Los Alamos, founded in 1876.
Set back from a busy street in the heart of the city you would never spot the house from the road.
Even though John Prescott, the deputy prime minister, highlighted the issue of road pricing, this week's document defines the heart of an integrated transport policy as better information and more reliable connections between various modes of transport.
Finally, on the eve of the last primaries in Montana and South Dakota, an article by Vanity Fair national editor Todd Purdum portrayed Bill Clinton as an angry, reckless individual who had been possibly "seeing a lot of women on the road, " and whose personality may have changed since a 2004 heart bypass operation.
"We're riffing on the joke about the chicken crossing the road, " explains Orchard when we meet at Studio AKA offices in the heart of London's Soho.
Mountain bikes designed for scrabbling along goat tracks or the heart of forests are as superfluous and unsuitable for our purposes as gigantic 4x4 off-road SUVs are on the school run.
Mr Begg can also take heart from the fact that repeated public opinion surveys have shown that motorists are willing to pay road charges for transport improvements.
The idea was that Elliott, who had won plaudits as the head of orthopedic joint maker Zimmer Holdings, could fix up a company whose main businesses in heart stents and implanted defibrillators, used to prevent sudden cardiac death, were running into significant road blocks.
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