This is despite the fact that deleting the SOR gene makes it impossible for the virus to replicate and would permit use of virtually all of the AIDS RNA to be used in the vaccine, minus the SOR gene.

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His tumor had a gene mutation being targeted by a new cancer vaccine being tested by Duke neurosurgeon John Sampson.

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Wong (now at Stanford University) figured the mutated gene might make an ideal target for a vaccine, as it creates an abnormal protein not seen in healthy cells.

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Some very cool science is on the drawing board: a recombinant vaccine that pairs salmonella with a gene from, say, the organism that causes tuberculosis as an oral delivery system to stimulate the body's natural immunity to both bacteria.

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Then, in the mid-1990s, he injected the vaccine into mice with tumors containing the mutant gene.

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By knocking out a gene essential to the parasite's development, Kappe hopes to create a vaccine against malaria.

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But it certainly is doing lots of novel science, including testing a vaccine for the biggest killer of children worldwide and e xotic new gene therapy.

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