The new combination had more side effects, such as infections and fever, than standard treatment, but quality of life was affected only during treatment and not afterwards.

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Dr Jane Jones, head of the HPA's travel and migrant health section, said there was no drug treatment for dengue fever.

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"All we can do is provide supportive treatment - relieving the fever, convulsions and so on, " says a senior clinician.

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Both drugs cause fever, aches and rash during and immediately after treatment.

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Excessive vomiting or sweating from fever can lead to dehydration, which is serious and requires treatment.

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Given its safety profile and how easy it is to make, it could quickly be tested as a potential new treatment for viral diseases ranging from dengue and yellow fever to hepatitis, say the US investigators from Georgetown University Medical Center in Washington.

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In malaria endemic countries, this will show that not all fevers are caused by malaria (much less than half) and the appropriate treatment can be given for whatever may be causing the fever.

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The side effects--fever, fatigue and anemia--are so bad that many patients forgo treatment, rolling the dice that their livers won't fail.

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Previous research into whether or not antibiotics are beneficial in the treatment of chest infections, where symptoms include shortness of breath, weakness, high fever, coughing and fatigue, have produced conflicting results- particularly in older people where chest infections can lead to further complications.

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