C-Sixty's fullerene-based drug scuppers this process by settling snugly into the enzyme's active site, stopping it functioning.

ECONOMIST: Nanotechnology in biology

Using this data, Adams in 1995 concocted an unusual boron molecule that snuggled into one of the enzyme's active sites and blocked its function.

FORBES: Magazine Article

These work by binding chemically to that enzyme's active site to inhibit its action. (Protease cuts the raw chain of virus protein produced by a subverted cell into functional molecules.) However, the mechanism is not quite identical.

ECONOMIST: Nanotechnology in biology

After a single cocaine dose, the enzyme that makes tyramine becomes more active in normal flies.

ECONOMIST: Flying high

Dr Wilson and his colleagues have discovered that the complex finds its way to the active site of a viral enzyme known as reverse transcriptase.

ECONOMIST: Nanotechnology in biology

Besides the evolutionary odds against such a drastic change happening, a big alteration in the shape of its active site might well render an enzyme and thus the virus ineffective.

ECONOMIST: Nanotechnology in biology

Yes, our bodies particularly an enzyme in our livers called CYP2D6 makes codeine active by replacing a part of the molecule to turn it into morphine.

FORBES: Why Codeine is Dangerous in Some Kids After Tonsillectomy