But some studies have looked at different end-points, such as death from all causes, or pneumonia or heart attack.
Primary end-points are needed for definitive (Phase 3) proof of efficacy, but they are the most pernicious concept in early stage development.
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Mike Lenhoff, a stock market strategist who is also from Brewin Dolphin, is optimistic about prospects for European equities for the rest of 2009 and has a year-end target of 5, 000 points for Britain's FTSE 100 all-share index, a level it has hovered around for the last month.
The game became an end-to-end spectacle with both teams sensing the three points could be theirs but chances went begging time and again.
We need to fight that year-end pressure to get points on the scoreboard.
Stoudemire looked rusty in his return, making just 3 of 8 eight shots -- one a dunk, another on a buzzer-beating 3-pointer to end the third quarter -- and finished with seven points and two rebounds.
Lastly, introducing high-end features breeds demand at the lower price points while Apple can learn how to maintain margins with higher-priced components.
In the third, Washington took a seven-point lead early in the quarter, but the Knicks scored nine straight points near the end and led 73-70 going to the fourth.
Based on cumulative five-year returns, the US trailed Europe by seven percentage points at the end of 2010, but by the end of 2011 was 20 points ahead a 27- percentage point swing in just one year.
Implied yields on 90-day bill prices slipped by three basis points along the curve and the lower yield environment spread to the long end where benchmark 10-year yields dropped by three basis points to 5.45%.
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The Kings got the lead to 18-6, but then Stoudemire had a dunk and three-point play on consecutive possessions, scoring seven points in a 19-4 burst to end the quarter that gave the Knicks a 25-22 lead.
Put simply, our enemies who share a fealty to shariah are perfectly capable - despite differences on fine points of Islamic practice - of collaborating to the common end of seeking our forcible submission to their doctrine or, failing that, to effecting our destruction.
Forest had seen their 19-game unbeaten run end at Derby last weekend but they have not dropped points at home since 7 November - and they showed the character and desire to grind out victory against the Owls even if the performance was below their recent standards.
Whereas religious and scientific apocalyptic subcultures converge and diverge on various points, there is one end-of-world scenario that manages to reflect all their anxieties: the zombie apocalypse.
Muni-yields fell mainly in the longer end where deals maturing between 23-30-years fell by six basis points.
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There could be an upside of 15% to our price estimate if the iPhone market share exceeds our current end-of-period estimate by about 4 percentage points.
Stylish and advanced, the new SL-Series models elevate the stature of the user-friendly family of digital cameras, allowing consumers to experience higher-end features and performance at more affordable price points.
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Both sides had chances to earn three points as the game turned into an end-to-end affair before finishing on equal terms.
The win helped Neil Lennon's side move on to five points in Group I, two behind joint-leaders Atletico Madrid and Udinese, while Rennes, who had Yann M'Vila sent-off towards the end, are bottom with two points.
And herein lies the nagging doubt that many SAP customers, influencers and employees still have: Can SAP can fully transform its old-school ERP ways in order to un-tether back end systems and deal with critical mobility pain points like security and scalability?
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Short-end bill prices fell sending implied yields higher by five basis points forcing the gradient of the curve higher as the steepening process grinds forward.
But after Chamberlain reached 69 points at the end of the third, an off-duty Associated Press photographer named Paul Vathis realized that history was in the air.
Helped by a worldwide slump in oil prices, he has managed to bring inflation down for four months running (see chart), even if the government's year-end target of 50% looks too optimistic by 15 percentage points.
The verdict brought an end to a messy proceeding, where the fine points of campaign-finance law were often overshadowed by witnesses crying on the stand or attorneys wrangling over how much could be said about a purloined sex tape or Ms. Hunter's menstrual cycle.
The yield on the benchmark 10-year Treasury is at 4.8%, down from 4.96% on Monday, an indication that investors are stampeding to the relative safety of U.S. government debt and away from corporate bonds rated Baa, whose yields have risen from 117 points above the 10-year Treasury at the end of last year to 134 above the mark as of Monday.
Since the end of 2000 short-term rates have been cut more than five percentage points in the U.S.--compare that with two points in the Eurozone (and in the U.K.) and only a quarter-point in Japan.
Stoudemire looked rusty in his return, making just 3 of 8 eight shots one a dunk, another on a buzzer-beating 3-pointer to end the third quarter and finished with seven points and two rebounds.
This measure, which we compute as the difference in interest rates between corporate bonds and 10-year Treasury bonds, fell from four points at the end of November to 3.3 points at the end of January, according to figures from Moody's.
In his final year, he appeared in all 82 games and averaged 20 points per, which put him among the (low-end of) league leaders.
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