Like Cymbalta, Effexor works by preventing the brain from reabsorbing the neurotransmitters serotonin and norepinephrine.
Of special importance to Lilly will Effexor, from Wyeth (nyse: WYE - news - people ).
He points out that Wyeth's largest products, including the antidepressant Effexor and Protonix, for ulcers, are the ones growing the fastest.
He rates the stock "underperform, " although he does see strength in some of Wyeth's drugs, including Effexor for depression, Protonix for acid reflux, and pneumonia vaccine Prevnar.
Prozac and its various descendents are a huge presence on our most-popular list, with Lexapro, Zoloft (No. 7), Cymbalta (No. 8) and Effexor (No. 10) all making appearances.
Later this year, Effexor could be hit by new competition from Cymbalta, a similar medicine being developed by Eli Lilly (nyse: LLY - news - people ).
The lawsuit opens a window into the ongoing debate about just how effective and safe the many newer-generation antidepressants are drugs including the huge blockbusters Zoloft, Prozac, Paxil and Effexor.
That also is creating doubts about whether Pristiq will be approved as an antidepressant, a major concern since Wyeth's top seller, the antidepressant Effexor XR, is expected to go generic next year.
However, he also said he expects strong sales of both Cymbalta and Effexor, and considers Lilly to be one of the best picks in the drug sector on the strength of its pipeline.
SNRIs include duloxetine (Cymbalta) and venlafaxine (Effexor).
CNN: Mixing migraine, depression drugs poses risk of serotonin syndrome
Wyeth sells Effexor, a widely used antidepressant, sells rheumatoid arthritis treatment Enbrel with Amgen (nasdaq: AMGN - news - people ) and has a pipeline stocked with new drugs, including an antibiotic the company thinks could be a blockbuster.
It is not the first drug to target both serotonin and norepinephrine--that honor goes to Effexor, a blockbuster made by Wyeth (nyse: WYE - news - people ) and put on the market around the same time as Prozac.
The current crop of drugs, including the big names such as Prozac, Celexa and Effexor, work by boosting levels of brain transmitters serotonin or norepinephrine or both, but they take several weeks to kick in and have side effects including sexual dysfunction.
Although more than half of the APCC's 10, 000 cat cases in 2012 involved exposure to insecticides and toxic cleaners that cats walked across and then ingested while grooming, there are certain medications notably, the antidepressant Effexor that cats will willingly consume, says Dr. Wismer.
For the most part, the prescription chatter concerns such familiar brands as Effexor, Wellbutrin, Xanax and Zoloft we're a long way from the Soma of Aldous Huxley's "Brave New World" though special attention is reserved for Ablixa ("Take Back Tomorrow"), a new competitor for market share that's no less effective for being fictional.
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