Patients who received the two-drug combination lived about 4.6 months longer without seeing their disease progress.
That's what happened in the 1990s with fen-phen, another diet drug combination that includes phentermine.
Furthermore, one can also envision fixed combinations of Januvia and ertugliflozin, which could prove to be an outstanding drug combination.
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Furthermore, on the basis of these results, this drug combination, known as Tredaptive, was approved for sale in Europe in 2008.
Kentucky lawyers Shirley Cunningham, William Gallion and Melbourne Mills, Jr. recruited some 440 clients after reports that fen-phen, a diet-drug combination, could cause life-threatening side effects.
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According to an AP report, the chemical keeps the drug combination intact until it binds to a cancer cell and delivers its anti-tumor cocktail.
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The world's first patient trial is using a drug combination of Thalidomide and chemotherapy to treat small cell lung cancer, the most deadly form of lung cancer.
Wyeth (nyse: WYE - news - people ) hoped the plan would cap its spiraling liability for fen-phen, the diet drug combination that has been linked to potentially fatal heart conditions.
"We will research a new drug combination therapy which aims to specifically target aggressive prostate tumours to control their growth and, most importantly, reduce the number of tumours which form in other areas of the body, " she said.
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The closest thing to a real success, a two-drug combination known as fen-phen, helped people lose as much as 30 pounds a year by making them feel satiated, but it caused heart valve problems in some and pulmonary hypertension in others.
The 12 patients who took Vertex's drug in combination with interferon and ribavirin showed no sign of the virus after four weeks of treatment.
Mark Levin , Millennium's CEO, has said that Velcade could eventually become a blockbuster, but only after new data come in on using the drug in combination with chemotherapy for more common cancers.
In the first stage of a phase III study called CLL11, the drug in combination with chemotherapy significantly reduced the risk of disease worsening or death compared to chemotherapy alone in previously untreated patients.
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Due to the lack of evidence of efficacy in early clinical trials, the drug (a combination of two proven cardiac medicines) had been rejected by the Food and Drug Administration nine years previously for approval for patients of all races.
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Additionally, GHSA is encouraging states to adopt an enhanced penalty for driving under the influence of multiple drugs, such as a combination of alcohol and another drug, or the combination of multiple drugs (other than alcohol).
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Pfizer manufactured the combination drug Prempro, one of the drugs in the 2002 study.
Meanwhile, a potent new combination drug from Novartis vanquishes malaria in three days.
And SpringLeaf set out to find investors that could appreciate the unique investment characteristics of its proposed drug-device combination.
Yesterday evening, Genentech released results of a midstage clinical test of its colorectal cancer drug Avastin in combination with chemotherapy.
Meanwhile, a potent new combination drug from Novartis (nyse: NVS - news - people ) vanquishes malaria in three days.
And now, the drug, in combination with the chemotherapy Taxol, allows patients with early-stage breast cancer an average of four months without their disease progressing.
Merck has been working to get the combination pill approved for several years and one critic is already saying it was a mistake to approve the combination drug.
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The use of combination drug therapy (two or more drugs) was also highest in the U.S. (64 percent compared with 44 percent to 59 percent in the European countries).
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Drugs that stimulate the next subtype, the 5-HT2B receptor, have been associated with heart valve disease, the major reason for withdrawal of the fenfluramine part of the fen-phen weight loss combination drug.
Currently, the FDA awards only three years of exclusivity if a fixed-dose combination drug contains a previously approved ingredient, and if a drugmaker conducted new clinical studies that were essential to approval.
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The watchword, borrowed from the jargon of drug delivery, is combination prevention.
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Dietary fat and simple-carbohydrate consumption be reduced in combination with drug therapy to lower the risk of pancreatitis for patients with severe and very severe hypertriglyceridemia.
However, he said it would almost certainly need to be a vaccine combining multiple "Achilles heels" - in the same way that HIV therapies are a combination of drug treatments.
Most patients taking PEG-Intron are given the drug packaged with Ribapharm 's (nyse: RNA - news - people ) ribavirin drug--the combination therapy can get rid of hepatitis C entirely in many patients.
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