The tumours were treated with two common components of chemotherapy - vinblastine or doxorubicin.
BBC: NEWS | Health | Cancer 'bouncers' keep drugs out
But those with high P-glycoprotein were up to 20 times more resistant to doxorubicin and up to 300 times more resistant to vinblastine.
They already have contributed to the development of the antibiotics erythromycin and tetracycline, the cancer chemotherapy drug doxorubicin, Wyeth's transplant drug Rapamune, and Merck's cholesterol-lowering medicine, Mevacor.
FORBES: A Dirty Business
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