The 23-year-old England international was fastest to react after captain Steven Gerrard forced a parried save from United keeper David de Gea just three minutes after Vidic's goal.

CNN: January 13, 2013 -- Updated 1910 GMT (0310 HKT)

Van Persie's sloppy ball saw Arsenal charge forward and Theo Walcott took advantage of a marginal call for offside to advance and beat David de Gea in the visiting goal.

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Tottenham almost drew level before halftime but winger Gareth Bale's powerful shot was well saved by David De Gea, after it had taken a slight deflection off defender Rio Ferdinand.

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Just before halftime, Carroll caught United goalkeeper David De Gea after going up for a corner -- a challenge that infuriated Ferguson, who later said it should have been a red card.

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Striker Villa hit the underside of the bar with only David de Gea to beat before the goalkeeper made a reaction save from Nicola Zigic's point-blank header and then tipped over another effort.

BBC: Hamburg and Atletico Madrid reach Europa League semis

The decisive moment came in the seventh minute, when the Honduras midfielder Roger Espinoza crossed from the left, and Jerry Bengtson jumped above Jordi Alba to power a header past Spanish goalkeeper David de Gea.

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Robin van Persie hit the crossbar and had another effort hacked off the line, while the much-maligned David De Gea produced an astonishing performance in the United goal, fending off every effort which came within his grasp.

CNN: Real held in Champions League blockbuster

Robin van Persie hit the crossbar and had another effort hacked off the line, while the much maligned David De Gea produced an astonishing performance in the United goal, fending off every effort which came within his grasp.

CNN: Real held in Champions League blockbuster

The European champions enjoyed more of the ball throughout the 90 minutes but they struggled to deal with the pace of Japan's attacks, with David De Gea, Manchester United's young goalkeeper, keeping his country in contention with several fine saves.

CNN: Spain suffer shock defeat to Japan