Scientists at Lilly say that Cymbalta may be more effective than Prozac ever was.
Because it is no longer experimental, Cymbalta is being removed from New Drugs To Watch.
Like Cymbalta, Effexor works by preventing the brain from reabsorbing the neurotransmitters serotonin and norepinephrine.
Just look at how well its antidepressant Cymbalta has done (See: The Most Prescribed Psychiatric Drugs).
By then, she was on the anti-anxiety drug Cymbalta and seeing a psychiatrist.
There is some room to debate how big a product Cymbalta will be.
She didn't like repeating messages like "Cymbalta is good for depression" over and over, and found that doctors tuned out such pitches.
Better yet, she says, Cymbalta may do a very good job of easing aches and pains, an area where other antidepressants haven't been tested.
Cymbalta, a newer type of antidepressant from Eli Lilly, lists only a 3% rate of ejaculatory dysfunction and a 6% rate of decreased libido.
That could lead to more delays, says Hazlett, but right now he expects both Strattera and Cymbalta to receive final approval in the second quarter of 2003.
Cymbalta represents an attempt by drugmaker Eli Lilly (nyse: LLY - news - people ) to re-establish itself in the market it built with Prozac.
Prozac and its various descendents are a huge presence on our most-popular list, with Lexapro, Zoloft (No. 7), Cymbalta (No. 8) and Effexor (No. 10) all making appearances.
Later this year, Effexor could be hit by new competition from Cymbalta, a similar medicine being developed by Eli Lilly (nyse: LLY - news - people ).
Madeleine Wohlreich , a clinical research physician at Lilly, notes that in company-run studies, patients on Cymbalta were 112% more likely to have their depression vanish than those who were on placebo.
However, he also said he expects strong sales of both Cymbalta and Effexor, and considers Lilly to be one of the best picks in the drug sector on the strength of its pipeline.
But when researchers conducted a clinical trial using a more exacting survey about sexual issues, called the Arizona Sexual Experience Scale (ASEX), they found that Cymbalta does cause increases in sexual side effects.
To market its medicine in a crowded field, Lilly is emphasizing that Cymbalta helps not only with the mental symptoms of depression but also with physical aches and pains that often accompany the disease.
SNRIs include duloxetine (Cymbalta) and venlafaxine (Effexor).
CNN: Mixing migraine, depression drugs poses risk of serotonin syndrome
Lilly (nyse: LLY - news - people ) moved a little farther along in its comeback story Monday when it received conditional approval from the U.S. Food and Drug Administration for Cymbalta, a new antidepressant.
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