When humans blossomed from the evolutionary tree, it seems there was a cold wet nose and a wagging tail waiting for us.

CNN: Quest for man's best friend

After that, the study subjects were quarantined for six days and given cold-virus-containing nose drops at a dose about 125 times the amount that it takes to infect cells in a laboratory.

CNN: Study: Can more sleep help fight off colds?

Whether Hemingway is jumping on a trampoline or submerging herself in a cold stream, with her pointed nose and bouncy blonde hair, her message in the film is one of achieving mental well-being and overcoming one's own problems.

CNN: Hemingway family mental illness explored in new film

About 43 percent of the volunteers had signs of infection plus cold symptoms, such as a stuffy nose, cough, and sore throat.

CNN: Study: Can more sleep help fight off colds?

To succeed, he will have to travel some 700 miles in temperatures cold enough to freeze the fluid in his nose and eyes, pulling the equivalent of two Sumo wrestlers up and down steep ridges while trying to avoid lethal gaps in the ice.

BBC: Sir Ranulph Fiennes: Up the Pole

The fatigue has been complicated by the fact that Obama has been battling a nasty cold, telling aides he feels like he's got an "acorn up my nose" -- an interesting turn of phrase I had never heard before but seems to mean the president is stuffed up.

CNN: Ed Henry: Obama in Europe -- Barack and a brandy

Matt Damon, looking more like a bullet than ever short hair, blunt nose, no stubble returns as the out-in-the-cold C.

NEWYORKER: The Bourne Ultimatum