Goldstein moved from Boston to San Diego in 2007 to establish San Diego Sexual Medicine, a 6, 000-square-foot facility with a sex therapist, physical therapist and a full clinical research facility where scientists study sexual dysfunction.

CNN: Sex is doctor's life's work

In this modern facility, company scientists are carrying out clinical trials on the 1, 300-year-old beauty secrets of China's only empress, Wu Zetian, who used skin potions made of motherwort.

NPR: Marketing to Millions: China's Changing Tastes

Chris Cline, vice president of clinical services at Skyland Trail, a mental health services facility in Atlanta, said it's not clear from Holmes' appearance whether mental illness is a factor.

CNN: STORY HIGHLIGHTS