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The big bottleneck in going from gene to drug is having the chemical know-how to create a small molecule drug, the kind of chemical that can be produced very cheaply and sold for a lot of money.
FORBES: Magazine Article
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They made every minor modification they could to that chemical, and came up with the MLN4670 molecule.
FORBES: Millennium Drug Bodes Well For Industry
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The firm's founders realised that biological synthesis of certain sorts of molecule is much more efficient than chemical synthesis.
ECONOMIST: Inhuman genomes
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Two lasers read fluorescent chemical tags that have been attached to the DNA molecule.
FORBES: Magazine Article
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Two lasers read chemical tags that have been attached to the DNA molecule.
FORBES: Technology
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The sugammadex molecule resembles a hungry octopus, with eight chemical arms that can grab the muscle relaxant already sold by Organon and put it into a mawlike hole.
FORBES: Magazine Article
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Because most small-molecule drugs can be manufactured with easily replicable chemical processes that lead to a largely reproducible drug formulation, the clinical trial data that supported approval of the original version can be relied upon for the generic versions.
FORBES: Commentary
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Each DNA molecule in the body contains two long strands of chemical letters, or bases--A, T, C and G--that come together like a twisted ladder (a.k.a. the double helix).
FORBES: Magazine Article
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To accomplish this unique approach, Organon chemist Anton Bom came up with a molecule that resembles a hungry octopus, with eight chemical "arms" that can grab the muscle relaxant and trap it in a maw-like hole.
FORBES: Magazine Article
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It's not well-known or even thought about but ever since Leo Hendricks unveiled the first fully synthetic moldable hard plastic called Bakelite to the American Chemical Society in 1909, except for a very small percentage that has been incinerated, every single molecule of plastic ever manufactured still exists somewhere in our environment.
CNN: Opinion: Creating a sea of change