Scholes picked up his first yellow card six minutes after the break, then Spurs striker Peter Crouch hit the crossbar before United's veteran midfielder received his marching orders for a second booking less than 10 minutes later.
But their task was made all the more difficult 10 minutes after the break as McCann was given his marching orders after picking up his second booking for a late tackle on Huddlestone.
The Welshman was also involved as Terry received his marching orders in the 67th minute, receiving his second booking after a late challenge on the pacy 20-year-old.