The companies that experienced the reductions are: Gilead Sciences Inc. ( GILD), Biogen Idec Inc. ( BIIB), Pall Corp. ( PLL), Onyx Pharmaceuticals ( ONXX) and Regeneron Pharmaceuticals ( REGN).

FORBES: Vanguard Health Care Fund Does More Shedding than Adding in Third Quarter

Biogen Idec Inc. ( BIIB - news - people ), experienced sharp upward shifts in share price as well as in options implied volatility following the news.

FORBES: Options Flash

Among the largest underlying components of IYH, in trading today Biogen Idec Inc ( NASD: BIIB) is up about 2.7%, Allergan, Inc ( NYSE: AGN) is up about 1.1%, and Covidien Plc ( NYSE: COV) is up by about 0.9%.

FORBES: IYH, BIIB, AGN, COV: ETF Outflow Alert

Among the largest underlying components of IBB, in trading today Gilead Sciences, Inc. ( NASD: GILD) is down about 0.5%, Celgene Corp. ( NASD: CELG) is off about 1.4%, and Biogen Idec Inc ( NASD: BIIB) is lower by about 0.8%.

FORBES: IBB, GILD, CELG, BIIB: Large Inflows Detected at ETF

Among the largest underlying components of IBB, in trading today Alexion Pharmaceuticals Inc. ( NASD: ALXN) is up about 0.1%, Biogen Idec Inc ( NASD: BIIB) is up about 0.8%, and Perrigo Company ( NASD: PRGO) is relatively unchanged.

FORBES: Notable ETF Inflow Detected - IBB, ALXN, BIIB, PRGO

Among the largest underlying components of XBI, in trading today Spectrum Pharmaceuticals Inc ( NASD: SPPI) is down about 1.9%, Onyx Pharmaceuticals, Inc. ( NASD: ONXX) is off about 1.2%, and Biogen Idec Inc ( NASD: BIIB) is lower by about 1.9%.

FORBES: XBI, SPPI, ONXX, BIIB: ETF Inflow Alert