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Danny Collins, Danny Pugh and Andy Wilkinson are all possible candidates to replace Higginbotham at left-back.
BBC: Stoke City visit Wembley ahead of FA Cup semi-final
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Andy Wilkinson, from the Environment Agency, said he was "keeping an eye on the River Glen".
BBC: Cars stuck in floodwater
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And with Danny Pugh and Andy Wilkinson man-on-man against Milner and Young, there was no space in behind for the wingers to exploit.
BBC: Lee Dixon's tactical view
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Andy Wilkinson blocked a low strike from Berbatov and Higginbotham bravely smothered a strike from Patrice Evra after the defender dribbled his way into the Stoke area.
BBC: Darren Fletcher put United in front
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Firstly, Danny Pugh came on for Andy Wilkinson, then Ibrahima Sonko for Ryan Shawcross and, finally, Ricardo Fuller was replaced by debutant Henri Camara after falling awkwardly and damaging his shoulder.
BBC: Sunderland 2-0 Stoke
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Pulis also accused an unnamed Newcastle player of feigning injury after a week in which his club came in for criticism following Andy Wilkinson's midweek challenge on Fulham striker Moussa Dembele.
BBC: Stoke face wait on Ricardo Fuller's shoulder injury
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The Stoke boss made four changes to the side which played out an uninspiring goalless draw against Sunderland, with Andy Wilkinson, Lawrence, Rory Delap and Fuller all drafted into the starting line-up.
BBC: Stoke 3-0 Blackburn
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The others are captain Phil Vickery, Mike Catt, Jason Robinson, Josh Lewsey, Jonny Wilkinson, Andy Gomarsall, Mark Regan, Martin Corry, Ben Kay, Lewis Moody and Joe Worsley, while Simon Shaw was a replacement but did not play.
BBC: Tindall & Hodgson miss World Cup
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Injured fly-half and new captain Jonny Wilkinson, veteran prop forward Jason Leonard and new coach Andy Robinson all received OBEs for services to rugby.
BBC: SPORT | Rugby Union | Queen honours England's Cup stars
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Wilkinson was appointed captain for England's three November internationals by acting coach Andy Robinson on Monday.
BBC: SPORT | Rugby Union | Internationals | Johnson backs Wilkinson
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In the injury-enforced absence of Jonny Wilkinson and Toby Flood, uncapped Leicester fly-half Sam Vesty and Brive's Andy Goode were selected ahead of Cipriani for the senior squad.
BBC: Cipriani defends form after axe