• The AIM-HIGH trial had enrolled high-risk individuals and all were prescribed statin drugs.

    FORBES: Lessons From Merck's Niacin Failure

  • These study results are quite remarkable and unexpected and will be one of the top CV stories of 2011, much as AIM-HIGH rocked the lipid community.

    FORBES: ALTITUDE Study of Aliskiren Terminated Early by Novartis

  • In 2011, the results of the AIM-HIGH study called into question the value of niacin in the treatment of cardiovascular disease in light of their inferiority to statins.

    FORBES: Vioxx and Diclofenac: Why Are Two Heart Risky Pain Drugs Viewed Differently?

  • Boden says that the Oxford researchers have contacted him about looking to see if any evidence of the side effect can be seen in the data for AIM-HIGH, but would not discuss the results further.

    FORBES: Why Merck's Niacin Failure Will Scare Drug Researchers

  • The study is particularly important because an NIH study, AIM-HIGH, was stopped earlier than expected, in April 2011, because it was so clear that the extended release niacin provided no benefits and continuing the trial would not be helpful.

    FORBES: Lessons From Merck's Niacin Failure

  • But William Boden, the University of Albany professor who ran AIM-HIGH, said it was too early to be certain which of the side effects seen in the study were due to niacin and which ones were due to laropiprant, the drug that Merck added to the combination.

    FORBES: Is This The End Of A Widely Used Heart Drug?

  • Armitage said that the trial results are unlikely to be due to the side effects of laropriprant, since the main finding of a lack of benefit is consistent with the AIM-HIGH study and many of the side effects are known to be associated with the use of niacin.

    FORBES: HPS2-THRIVE: A 'Disappointing But Clear' Result

  • They aim for high-level events that spark creativity and education opportunities.

    FORBES: Where Education and Entrepreneurs Meet

  • Ward Walkers is a privately-owned firm established in Dundee in 2004 with the specific aim of delivering high-quality work shoes to the nursing profession.

    BBC: Dundee shoe firm Ward Walkers secures NHS contract

  • We aim to not only open more high-quality public schools across the country but also to have a transformative impact on the traditional school system.

    FORBES: Magazine Article

  • The aim is to curb the sort of high-risk lending that contributed to the financial crash in 2008.

    BBC: EU tightens up bank lending rules and bonuses

  • The Joker wreaks havoc across Gotham City with no apparent aim, leading to spectacular explosions, high-rise confrontations and a spine-chilling character study from Ledger.

    BBC: Batman's nemesis crowns dark tale

  • So to keep up with its more valuable rival, Dell is taking aim again at the high-end niche dominated by Apple, adding another pair of redesigned laptops to its high-end XPS portfolio Tuesday.

    FORBES: Dell Sends Redesigned XPS Notebooks Back Into Battle With Apple

  • His aim has been to run a low-cost airline with high standards, both in terms of cleanliness and reliability.

    CNN: Is ego the reason for India's airline woes?

  • Having said that, Mr Crane does also believe that the Obama presidency might help inspire black youngsters to aim high in life and work for more change - and he will be watching the inauguration.

    BBC: Black Washington looks to Obama

  • Both products aim to marry the popular low-volatility strategy with the similarly popular high-yield equity strategy.

    FORBES: Dividend ETF Party Getting Pretty Crowded

  • However as I left with the assurance that the family and friends would take great care of her, an old aunt pulled me to one side and told me to aim high, there's room for everyone up there -- a motto which has stayed with me always.

    CNN: STORY HIGHLIGHTS

  • The hassle of having to explode a nuclear bomb every time a beam was needed meant the idea never went anywhere, though it did spur research into high-powered chemical lasers and the sophisticated optics needed to aim and control them.

    ECONOMIST: Energy weapons: Zap, crackle and pop | The

  • Before the award ceremony they explained that the training sessions - where they are surrounded by international athletes from several disciplines - inspire and encourage them, and give them the ideal preparation to aim high in the coming season.

    BBC: Kevin Borl��e wins Golden Spike

  • More than half of the nation's state legislatures have had measures introduced that aim to nullify the effect of any federal ban on firearms, assault weapons and high-capacity ammunition magazines, according to data collected by the he National Conference of State Legislatures.

    CNN: Will states go where Congress hasn't on gun laws?

  • With the first period half over, the student took direct aim and hit one classmate in the 28-student classroom in the science building of Taft Union High School in Taft, California, authorities said.

    CNN: STORY HIGHLIGHTS

  • Her organization connects high school students with underprivileged youths through collaborative hands-on science experiments, with the aim of inspiring all participants to pursue higher education.

    WHITEHOUSE: The White House

  • The same report criticized both parties for their fundraising efforts, taking aim at Republicans for going outside the host committee to drum up cash and the Democrats for having a high-profile lobbyist in charge of convention fundraising.

    FORBES: Delegates, Welcome To Lobbypalooza 2008

  • "I believe that in its final version, the act will deliver on its central aim - to bring the interests of us all as citizens and consumers to the fore, while increasing investment and maintaining high standards, " said Ms Jowell.

    BBC: Media bill becomes law

  • Genentech and Novartis initially plan to aim Xolair at 500, 000 or so moderate-to-severe asthmatics whose condition isn't controlled even with high doses of existing drugs, such as GlaxoSmithKline 's (nyse: GSK - news - people ) inhaled steroid Flovent or Merck 's (nyse: MRK - news - people ) Singulair, a so-called leukotriene inhibitor.

    FORBES: Magazine Article

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