Negative briefing documents from FDA staff hardly represent a death knell for a drug.
The Fitch credit agency has taken away its triple-A rating, a veritable death knell for a bond insurer.
Yet while many have heard a death knell from the Web, the advent of free papers may prove a promising source of revenue for increasingly desperate newspaper publishers.
What is a boon to us consumers is a death knell for computer companies.
It is not clear to me that this would be a death knell for the industry.
Now, with many banks still weakened by the financial crisis, the regulation could be a death knell.
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This is firstly something of a death knell for organic farming: we know that that is more land hungry than conventional farming.
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It means a death knell for Leyton Orient, London's second-oldest club.
Even though Amazon had portrayed the encroachment of local sales taxes as a death knell, it appears that it has actually presented them with an opportunity to become even more Amazonian: more locations.
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In 1987 the Court dealt a death knell to the denial of services fraud doctrine, limited the mail and wire fraud statutes to protection of tangible property rights and challenged Congress to fix the problem if it wished to do so.
Considering that Apple derives over 70% of its profits from iPhones, such a scenario will be a virtual death knell.
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Lord Justice Leveson, sepulchral in tone, has delivered conclusions that could, or so many fear, become the death knell of a free press.
He himself has recently been opening plants in Slovakia and the Czech Republic and sounding the death-knell for a factory in Britain that closed its doors last month.
Both Pittman and Knell arrive following a period of turmoil, as new CEOs often do.
An ad attacking Pat Toomey, the Republican candidate for the Senate in Pennsylvania, chides him for praising Chinese growth, while a gong booms like the knell of doom.
Plans for a new Costa Coffee shop on Gloucester Road in Bristol will sound the "death knell" for the area, according to a 3, 000-name petition.
Going further, he believes the ID card scheme in its current form could sound the death knell for government services online at a time when they are just beginning to be adopted by people.
Plans to build a supermarket on a Staffordshire park, could sound the "death knell" for an annual food and drink festival, organisers have said.
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The meeting is a significant move and it is not the first time that Al-Azhar, a highly-respected Sunni Muslim institution, has intervened to help solve a political crisis, the BBC's Yolande Knell reports from Cairo.
And commentators of all stripes are arguing that sending the army back into Gaza, less than a year after it was pulled out, is the death-knell for Mr Olmert's plan to withdraw from most of the West Bank.
As the most populous Arab country and a historic regional heavyweight, Egypt, a predominantly Sunni power, has in the past seen itself as a political rival of Shia Iran, says the BBC's Yolande Knell in Cairo.
Although email has gone from after-school treat to a dull routine in the space of 20 years, no one is ready to ring its death knell just yet.
They also agreed that poorly executed pricing strategies can be the death knell for retailers, and could end up lowering the water mark for the industry as a whole.
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Arvind Subramanian, an economist at the Peterson Institute for International Economics, a think-tank in Washington, DC, argues that the recession in eastern Europe sounds the death knell for one of the two main growth strategies of the past 20 years capital-account liberalisation (growth through exports is the other).
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