一种定位和剪开基因链的方法叫做“锌指”——由基因链组成的蛋白质,它可以通过高特异性辨识到DNA的“接头”,并和DNA相互连接起来。
One approach for locating and snipping DNA strands involves "zinc fingers" - proteins that bind to DNA and can be linked together to recognise extended stretches of DNA with very high specificity.
多重生化过程带来了蛋白质分子的化学修饰,并通过与定位在细胞某一区间的独特结构发生联系,使化学修饰进一步多样化。
Multiple biochemical processes create chemical modifications of protein molecules, further diversified by association with distinct structures at defined locations of a cell.
在这项研究中,马里兰州国家癌症研究所的研究员们,使用一种能够定位癌细胞表面蛋白质的抗体。
In this study, researchers at the National cancer Institute, Maryland, used an antibody which targets proteins on the surface of cancerous cells.
蛋白质-蛋白质之间的关系与蛋白质的胞内定位对它们的功能发挥有着长远影响。
Protein-protein interactions and protein localization within the cell can have profound influence on protein function.
在悉尼的会议上,贺福初计划拿出未公布的蛋白质-蛋白质相互作用以及定位的相关数据进行讨论,他说:“这是真的,会对其他组织器官的综合性论证产生积极影响。”
At the Sydney meeting, He plans to discuss unpublished work that maps protein–protein interactions and their localization. "It's a real, comprehensive demonstration for other organs," he says.
线粒体约含1 000种左右蛋白质,其中98%以上系由细胞核编码,在细胞质核糖体上以前体形式合成之后再运至线粒体并选分定位于各部分。
About 98% of the 1 000 or so mitochondrial proteins are encoded in the nucleus and synthesized on cytosolic ribosomes as precursors, which are then imported into mitochondria.
背景:亚细胞定位信息是蛋白质功能研究的关键特征之一。
BACKGROUND: Subcellular localization information is one of the key features to protein function research.
第三章为蛋白质亚细胞定位的预测。
The third chapter gives the prediction of protein subcellular location.
利用蛋白质中氨基酸组分,通过计算离散增量和离散有限系数预测蛋白质的亚细胞定位。
By use of proteins amino acid composition, the subcellular location of a protein can be predicted by calculating increment of diversity and finite coefficient of diversity.
其次,我们探索了亚细胞位置之间的依赖关系,并且将这种关系用于支持向量机来进行蛋白质亚细胞定位。
Second, we explore the interdependences between subcellular locations and incorporates them with SVMs for prediction of protein subcellular localization.
随着后基因组时代的来临,蛋白质序列信息增长迅速,而利用实验手段分析蛋白亚细胞定位的不易大规模进行。
With the advent of the post-genome era, the rapid enlarge of protein sequence information, it is difficult to use experimental methods in large-scale analysis of protein subcellular location.
蛋白质n -糖基化生物过程和相关的许多酶主要定位于胞浆内质网和高尔基体。
The reactions of the protein N-glycosylation pathway occur along the secretory pathway and most of the entail enzymes localized in the endoplasmic reticulum and the Golgi body.
用来确定蛋白质的最终亚细胞定位的很多信息是在它们的氨基酸序列中找到的的观点已经得到了广泛地认同。
It is widely recognized that much of the information for determining the final subcellular localization of proteins is found in their amino acid sequences.
植物蛋白质的亚细胞定位是功能基因组学的重要内容。
Protein subcellular localization is one of the key questions for functional genomics.
蛋白质组学研究直接定位于蛋白质水平,从整体、动态、定量的角度去研究基因的功能,是后基因组计划的一个重要组成部分。
Proteomic research is to reveal the function of genes from an integrated, kinetic and quantitative view at the global protein level, which is an important component of post genome project.
并对被鉴定的差异蛋白质进行功能和定位的分类分析。
Cellular location and function of these identified differential protein were classified.
这些蛋白质可能参与Crk1的成熟、转运、定位以及活性调控。
These proteins may be involved in maturation, transport, localization, and activity regulation of the Crk1.
利用某些蛋白酶对食品蛋白质的定位水解而可产生具有降血压活性的短肽。
Some proteases hydrolyze some food proteins at certain peptide bonds and produce short peptides having antihypertensive activity.
蛋白质组学是研究蛋白质的表达、翻译后修饰、在细胞内定位以及蛋白质与蛋白质之间的相互作用的科学。
Proteomics is a subject that aims to study the expression, translation and location of proteins, the relationship between proteins and proteins as well.
我们在关于蛋白质亚细胞定位和远同源性检测的两个不同的数据集上做了实验。
We report experiments on two data sets, predicting subcellular localizations and remote homology detections.
现对定位于外膜、基质和内膜的蛋白质的运送途径的研究进展作一扼要介绍。
The import machinery of mitochondrial proteins which are located in the outer membrane, matrix or inner membrane is described in this review.
目的利用重组的胞内氯离子通道蛋白clIC1蛋白的过表达来了解该蛋白质在细胞中的定位。
Objective To investigate the localization of recombinant CLIC 1 protein in cultured cell line with its overexpression.
人类基因组计划的测序工作完成之后,已进入后基因组学阶段,疾病基因的定位克隆及其蛋白质功能研究已成为研究的重要内容。
IntroductionPositional cloning of disease genes and research of protome become very important in the post-genome period after completion of human genome project( HGP).
蛋白质处于特定的亚细胞位置上才能行使其功能,故研究亚细胞定位对了解蛋白质功能非常重要。
Protein can work only in specific subcellular position, so where the protein located in a cell is very important for the study of the protein functions.
摘要:蛋白质的亚细胞定位信息对于深入了解该蛋白质的功能具有重要意义。
Abstract: The information of protein subcellular localization is important to our understanding of a protein function.
蛋白质的亚细胞定位信息对于深入了解该蛋白质的功能具有重要意义。
The information of protein subcellular localization is important to our understanding of a protein function .
结果成功鉴定到43个磷酸化蛋白质,其中有14个定位于膜上。
In this study, 43 phosphoproteins were identified, among which 14 proteins were located on the membrane.
结果成功鉴定到43个磷酸化蛋白质,其中有14个定位于膜上。
In this study, 43 phosphoproteins were identified, among which 14 proteins were located on the membrane.
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