根据动物实验来预测人体的药物代谢时,代谢酶的种属差异性会使这项研究工作变得非常困难。
Predicting of drug metabolism in humans based on animal experiments is complicated by species differences in the catalytic properties of these enzymes.
然而IL - 1受体拮抗剂治疗骨关节炎的临床实验仅取得有限成功,研究人员认为主要是因为药物代谢太快。
However, trials of IL1RA for osteoarthritis have had limited success, primarily because the drug tends to break down quickly, according to the researchers.
结论大鼠原位肝灌流是良好的整体器官药物代谢模型,是体外实验有力的补充。
CONCLUSION In situ liver perfusion is an appropriate organ model for drug metabolism and disposition research.
同时实验还表明,山药促进剂对内源性蛋白溶菌酶以及外源性蛋白溶菌酶药物代谢没有明显影响。
The experiments also indicate that the yam accelerant has no obvious influences on the metabolism of endogenous protein lysozyme and exogenous protein lysozyme drugs.
实验目的:以正常饮食和药物干预为对照,观察8周有氧运动对高脂饮食大鼠血脂代谢的影响。
To investigate the effect of 8-week aerobic exercise to rats' serum lipids fed with high-fat-diet, compared with Normal and Medicine groups.
实验目的:以正常饮食和药物干预为对照,观察8周有氧运动对高脂饮食大鼠血脂代谢的影响。
To investigate the effect of 8-week aerobic exercise to rats' serum lipids fed with high-fat-diet, compared with Normal and Medicine groups.
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