• 南瓜蛋白及其同类物肿瘤机制提供理论基础肿瘤诱导分化疗法提供新线索。

    To provide some theoretical foundation on anticancer mechanism of cucurmosin and its analogues, and provide a guide to differentiation-inducing therapy for cancer.

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  • 目的观察损伤组织萃取人肝癌细胞株bel- 7402影响探讨肿瘤诱导分化治疗途径

    AIM: To observe the effects of tissue extracts of injured liver on BEL-7402 cells, and explore a novel strategy of tumor therapy by differentiation induction.

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  • 目的建立肿瘤细胞诱导分化模型

    Objective To set up a cell model of human tumor cell inducing differentiation.

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  • 除了局部免疫发挥作用外,各种因素诱导产生的抗菌还参与细胞分化组织修复肿瘤等功能。

    In addition to their role in immunity, some antibacterial peptides can play the distinct roles in cell differentiation, tissue repair and antitumor immunity.

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  • 目的临床试验组蛋白脱乙酰基酶阻滞剂(HDACi)研究目的在于诱导细胞分化生长停止肿瘤细胞凋亡

    Purpose: Histone deacetylase inhibitors (HDACi) are being studied in clinical trials with the aim to induce cellular differentiation, growth arrest, and apoptosis of tumor cells.

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  • 结论ATRA并不能诱导HL-60细胞完成终端分化但是该药可以诱导白血病细胞向成熟方向分化而且分化肿瘤细胞发生凋亡

    CONCLUSION: ATRA cannot induce HL 60 to achieve terminal differentiation, but the differentiation of HL 60 can be induced by ATRA and the differentiated leukemia cells are easy to apoptosis.

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  • 分化诱导广泛应用于肿瘤研究肿瘤预防治疗方面取得一定进展其中以维甲酸类药物效果肯定。

    Agents that induce cell differentiation have been widely used in tumor research and achieved progress in the prevention and treatment of tumor. among them, retinoid drug shows confirmative effect.

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  • 结论APS可能成为促进正常造血能抑制白血病等肿瘤细胞增殖诱导凋亡或分化天然诱导剂。

    Conclusion: APS may not only promote normal hematopoiesis, but also inhibit the proliferation of leukemia cell and it can be a natural inducer for therapy of malignant tumor.

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  • 目的肿瘤诱导分化疗法肿瘤治疗研究领域

    Objectives the induction of differentiation therapy for cancer is a new field in the research of tumor treatment.

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  • 捕获肿瘤抗原后,DC迁移TDLN,发育成熟递呈抗原,诱导T细胞分化成熟杀伤肿瘤细胞。

    After capturing tumor antigen, DC migrates to TDLN where it becomes matured and starts presenting antigen, then induces t cell differentiation, maturation and to kill tumor cells.

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  • 目的研究肿瘤细胞分化诱导剂尿多酸肽(CDA - II)胃癌细胞体外抑制作用

    Objective: to study the inhibitory effect of Uroacitide (CDA-II) on human gastric cancer cell in vitro.

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  • 结论丁酸其它诱导分化联合应用可能部分血液肿瘤有效诱导分化治疗方法

    Conclusion Phenylbutyrate combined with other differentiation agents may be an effective differentiation therapy in a proportion of hematological malignancies.

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  • 近年来,出现了诱导分化凋亡治疗手段,在某些肿瘤治疗上取得了可喜效果

    Recently, leading differentiation and apoptosis were found, and of a few clinical practice had proved their effect.

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  • 诱导分化分化诱导存在恶性肿瘤细胞形态、生物学或生物化学方面的诸多标志均正常细胞的方向分化甚至完全转变成正常细胞

    By derived differentiation, we mean that under the effect of differentiation inducer, malignant tumor cell has the tendency to differentiate to normal cell, even became normal cells.

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  • 目的研究小鼠骨髓干细胞体外诱导分化树突状细胞T细胞增殖影响进一步研究树突状细胞的功能及临床肿瘤治疗提供有效的实验方法

    Objective To study the effects of mature dendritic cells (DCs) derived from mouse bone marrow on T cell proliferation in vitro, and provide techinological methods for tumor therapy.

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  • 结论全反式维甲酸具有调控分化相关基因表达与否的重要作用,由RA诱导肿瘤细胞再分化一个基因参与过程

    Conclusion ATRA plays an important role in regulating the differentiation-related gene expression. ATRA-induced differentiation is a complex process with multiple genes involved.

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  • 目的 观察藤黄酸对肿瘤细胞诱导分化作用

    Time effect on differentiation of neural stem cells to dopaminergic neurons;

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  • 目的 观察藤黄酸对肿瘤细胞诱导分化作用

    Time effect on differentiation of neural stem cells to dopaminergic neurons;

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