本发明还提供了该缓释微球制剂的制备方法。
The invention also provides the preparation method of the slow release microsphere agents.
结果:电纺技术制备出具有一定力学强度的缓释微球的纤维膜。
Results: Making use of this new method, a new periodontal tissue regeneration membrane with higher mechanical strength can be prepared.
目的研究以壳聚糖和阿拉伯胶为基质,制备尼莫地平缓释微球的工艺。
Purpose To study the method which was used to prepare nimodipine microspheres with chitosan-Gum-arabic by means of a complex coacervation method in an emulsion system.
结果与结论多肽、蛋白质药物缓释微球在药学领域有着广阔的发展前景。
Results and Conclusions Polypeptide-protein microspheres have broad prospects in the pharmaceutical filed.
缓释注射剂由缓释微球和溶媒组成,溶媒分为普通溶媒和含有助悬剂的特殊溶媒。
The sustained-release injection is composed of sustained release microspheres and menstruum, and the menstruum is classified into common menstruum and special menstruum with suspending agent.
公开了一种使用喷雾干燥制备缓释微球的方法,所述微球包含作为载体的生物可降解聚合物和药物。
The present invention discloses a process of preparing sustained release microspheres, containing a biodegradable polymer as a carrier and a drug, using spray drying.
该方法制备的左氧氟沙星-壳聚糖缓释微球载药量为43.88%,体外累积释放度的线形关系良好。
The drug-loading rate of this chitosan-levofloxacin sustained-release microsphere is 43.88%. Its in vitro dissolubility is good.
方法采用固体分散载体和阻滞性高分子材料,使用固体分散与球晶制粒相结合的技术制备水飞蓟宾缓释微球。
Methods Sustained-release silybin microspheres were prepared by the spherical crystallization technique with solid-dispersing and release-retarding polymers.
结论BCNU PLGA缓释微球可以抑制C6胶质瘤细胞的增殖,随释放时间延长细胞生长抑制率逐渐上升。
Conclusion BCNU loaded PLGA wafer can inhibit the proliferation of C6 glioma cell and demonstrate gradually increased tendency with prolonged release time.
结果:抗菌药物脂质体、纳米球、微球等可提高感染细胞或组织的药物浓度,同时具有缓释特性,延长有效药物浓度维持时间。
Results: the newer delivery systems increased drug concentration in infected cells or tissue, having slow release and lengthen of effective drug concentration.
结果表明,后二法制备的微球缓释效果明显。
The results showed the microspheres prepared by these two methods had obviously sustained release effect.
结论布洛芬聚乳酸微球在一定浓度下可以作为一种局部缓释药物应用于颅内。
Conclusion: The ibuprofen polylactide microspheres could be used as a local slow release drug in cranial under a certain concentration.
本文还对三种微球缓释效果的不同原因进行了分析。
The reasons with different release effects were also discussed.
结论本法准确可靠,操作简便,适用于缓释bcnu微球的体外药物释放动力学研究。
Conclusion This high performance liquid chromatography method is simple, sensitive and accurate. It is suitable for released kinetics study of controlled-release microspheres of BCNU loading in vitro.
目的运用灰色数学理论预测长效缓释蛋白微球的体外释药过程。
OBJECTIVE To predict drug release from the extended formulations by grey maths model.
目的考察低分子肝素肺靶向微球缓释性、稳定性和靶向性。
AIM To test gelatin microspheres of low molecular weight heparin (LMWH-GMS) release behavior; lung target behavior and stability.
结论:微球的制备工艺满意,与原药相比,微球对小鼠有明显的缓释、延长抗生育时间和降低毒性的作用。
CONCLUSION: The technology of preparation was successful and the anticonceptive effect in mice was satisfactory with much lower toxicity as desired.
结果:该微球具有良好缓释效果。
Results: The microspheres had a property of sustained drug release.
结论:聚乳酸大蒜素微球具有良好的缓释作用。
Conclusion: Diallyl trisulfide microspheres have obviously sustained effect.
当空心微球包裹有药物、酶或催化剂时,可应用于药物缓释、酶固定化和催化剂领域。
The hollow microsphere can be applied in the fields of drug controlled release, enzyme fixation and catalyst when wrapping drug, enzyme or catalyst.
近年来国内外研制成缓释、控释制剂的主要有片剂、胶囊剂、微球剂、滴眼剂、注射植入剂等。
In recent years, many sustained-released and controlled-release agents have been prepared successfully internal and abroad, such as tablets, capsule, micro spheres, eye drops, injection implant etc.
结论所制微球具有很好的缓释作用,操作方便,工艺稳定,有利于工业化生产。
ConclusionThe microspheres sustained released well in vitro and in vivo and its convenient preparation is suitable for industrialization and production.
结论所制微球具有很好的缓释作用,操作方便,工艺稳定,有利于工业化生产。
ConclusionThe microspheres sustained released well in vitro and in vivo and its convenient preparation is suitable for industrialization and production.
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