目的探讨细胞周期抑制剂对脑神经细胞凋亡的影响。
Objective to study the effect of cell cycle inhibitor on apoptosis of cerebral neurons.
目的:研究泛素蛋白酶体抑制剂对胃癌细胞增殖和凋亡的影响。
AIM: to investigate effects of ubiquitin-proteasome inhibitor on proliferation and apoptosis of gastric carcinoma cells.
吉非替尼为一种选择性的EGFR一蛋白酪氨酸激酶抑制剂,能阻断酪氨酸蛋白激酶信号传导通路,从而促进肿瘤细胞凋亡。
Gefitinib is protein tyrosine kinase inhibitor of a selective EGFR, can block the signal transduction pathway of tyrosine protein kinase, and then promote tumor cell apoptosis.
结论:NOS抑制剂通过减轻缺血缺氧脑损伤时胎鼠脑神经细胞凋亡对其出生后的远期智能起保护作用。
Conclusion: NOS inhibitors play a obvious protective role in long-term intelligence of fetal rat after delivery through relieved neuron apoptosis during hypoxic ischemia encephalopathy.
目的探讨蛋白酶体抑制剂MG- 132对体外人u87胶质瘤细胞增殖和凋亡的影响。
Objective to explore the effects of proteasome inhibitor MG-132 on proliferation, apoptosis of U87 glioma cells in vitro.
结论:选择性COX - 2抑制剂体外可抑制T24细胞的增殖,并诱导细胞凋亡。
CONCLUSIONS: Selective COX-2 inhibitor could inhibit the proliferation and induce the apoptosis of T24 cells.
选择性COX - 2抑制剂体外可抑制膀胱癌细胞的增殖,并诱导细胞凋亡。
Selective COX-2 inhibitors could suppress the proliferation and induce apoptosis of bladder cancer cell line.
蛋白酶体抑制剂可选择性地促进肿瘤细胞凋亡,逆转多药耐药。
Proteasome inhibitors can selectively promote the apoptosis of tumor cells and overcome MDR.
目的评价5脂质加氧酶(5LOX)代谢途径在胃癌中的作用及5 LOX抑制剂对胃癌细胞凋亡的影响。
Aim to evaluate the effect of 5 LOX pathway in gastric cancer and the potential role pharmacological inhibition of 5 LOX on induction of apoptosis in gastric cancer cells.
目的:探讨组蛋白去乙酰化酶抑制剂MS- 275诱导人多发性骨髓瘤细胞株u266凋亡的分子机制。
OBJECTIVE: to investigate the molecular mechanisms of histone deacetylase inhibitor MS-275 on apoptosis of human myeloma U266 cell line.
结论:蛋白酶体抑制剂mg132能够抑制多巴胺能细胞PC 12的增殖并诱导细胞凋亡,蛋白酶体活性的丧失可能影响到多巴胺能细胞的生存。
CONCLUSION: MG132 can inhibit the proliferation of dopaminergic PC12 cells and lead to apoptosis. The disfunction of proteasome may do harm to the existence of dopaminergic cells.
金雀异黄素是一种天然的酪氨酸激酶抑制剂,可以抑制多种肿瘤细胞的增殖,并诱发细胞凋亡。
Genistein, a natural tyrosine kinase inhibitor, has been reported to inhibit growth and induce apoptosis of various Turner cells.
细胞渗透、有效的蛋白磷酸酶抑制剂。凋亡诱导剂。两种异构体的混合物。
Cell permeable, potent protein phosphatase inhibitor. Apoptosis inducer. Mixture of two isomers.
经实验证实,该类化合物可作为细胞增殖抑制剂、细胞凋亡诱导剂或抗肿瘤剂。
Experiments prove that the compounds can be used as a cell proliferation inhibitor, an apoptosis inducer or an antitumor agent.
经实验证实,该类化合物可作为细胞增殖抑制剂、细胞凋亡诱导剂或抗肿瘤剂。
Tests prove that the compounds can be used as a cell proliferation inhibitor, an apoptosis inducer or an anti-tumor agent.
嗜热菌杀酵母素通过耗尽细胞的鞘脂类诱导凋亡,抑制白介素2依赖性的小鼠毒性细胞的增殖,是一种有效的免疫抑制剂。
Myriocin induces apoptosis by depletion of cellular sphingolipids, inhibits proliferation of IL-2-dependent mouse cytotoxic cells and is a potent immunosuppressant.
目的筛选细胞凋亡相关疾病中重要靶点——卡斯帕酶-3抑制剂。
OBJECTIVE To screen inhibitors of caspase-3, which is a key enzyme responsible for diseases related to cell apoptosis.
本发明的长链烃基取代苯酚类化合物可作为细胞周期抑制剂、细胞凋亡诱导剂、细胞增殖抑制剂和抗肿瘤剂用于抗肿瘤治疗。
The disclosed compounds can be used as cell cycle inhibitor, cell apoptosis inducer, cell proliferation inhibitor and antineoplastic agent in tumor-resisting treatment.
本发明的长链烃基取代苯酚类化合物可作为细胞周期抑制剂、细胞凋亡诱导剂、细胞增殖抑制剂和抗肿瘤剂用于抗肿瘤治疗。
The disclosed compounds can be used as cell cycle inhibitor, cell apoptosis inducer, cell proliferation inhibitor and antineoplastic agent in tumor-resisting treatment.
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