酪氨酸576和酪氨酸577处于激酶结构域的激活环，这些残基的突变减弱FAK的催化活性（6）。
Tyr576 and Tyr577 lie in the activation loop of the kinase domain, and mutation of these residues reduces FAK catalytic activity (6).
和LSD1相似的是，其高度保守的SWIR M结构域是其酶活性所必需的。
Like LSD1, the highly conserved SWIRMdomain is required for its enzymatic activity.
极光激酶A催化结构域苏氨酸（288位）的磷酸化能够增强激酶的活性。
Phosphorylation of Aurora A at Thr288 in its catalytic domain increases kinase activity.
他们发现，在较大比例患有肺癌的病人中，可以激活EGFR的特定突变能导致激酶结构域活性增加20倍。
They found that a particular mutation that activates EGFR in a large percentage of patients with lung cancer caused a 20-fold increase in the kinase domain's activity.
目的：表达与提纯R IZ1第1个至第200个氨基酸含PR结构域的活性GST融合蛋白质（GST-PR200融合蛋白）。
Objective To express fusion protein of GST and 1-200 residue region containing PR domain of human RIZ1 protein(GSTPR200 fusion protein).
目的：表达与提纯R IZ1第1个至第200个氨基酸含PR结构域的活性GST融合蛋白质（GST-PR200融合蛋白）。
Objective To express fusion protein of GST and 1-200 residue region containing PR domain of human RIZ1 protein(GSTPR200 fusion protein).
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