靶抗原表位可能位于N -糖链上。
其抗原表位主要是蛋白质或多肽。
信号肽;金属蛋白酶;抗原表位;
目的:分析患者血清中抗hcv抗体的抗原表位。
Objective: epitope analysis of anti-HCV antibodies isolated from patients serum.
通过噬菌体肽库技术分析抗体所识别的抗原表位。
The mAb epitope was also analyzed using peptide phage display technology.
目的从噬菌体肽库筛选日本血吸虫抗原模拟抗原表位。
Objective To screen the mimic antigen epitopes of Schistosoma japonicum from phage display peptide library.
本发明公开了一种幽门螺杆菌尿素酶B抗原表位多肽及其应用。
The invention discloses a helicobacter pylori urease B antigen epitope polypeptide and application thereof.
本发明公开了一种幽门螺杆菌尿素酶B抗原表位多肽及其应用。
The invention discloses a helicobacter pylori urease B antigenic epitope polypeptide and application thereof.
实验表明,用基因工程表达的多肽筛选抗原表位的方法是可行的。
The method based on expressed peptide for mapping epitope on viral prot…
设计了一种新的病原体蛋白质B细胞抗原表位的筛选和重组表达方法。
A novel method was designed for disease specific B cell epitope mapping and epitope expression in e.
竞争抑制实验表明所获人源抗体片段与亲本鼠源单抗结合同一抗原表位。
Binding competition studies demonstrated that they bound the same epitope of the Ag as the parental Ab.
有关病原体、毒力因子和抗原表位的信息的编纂产生了很多有用的数据库。
The compilation of information concerning pathogens, virulence factors and antigenic epitopes has resulted in many useful databases.
目的:利用噬菌体展示肽库技术筛选鸡传染性支气管炎病毒的模拟抗原表位。
Objective:To obtain the mimotope of avian infectious bronchitis virus by phage display peptide library.
目的:为了探讨噬菌体展示技术在筛选和鉴定病毒抗原表位研究中的应用前景。
Objective: to investigate the possibility of application of phage display technique in screening and identifying the virus antigenic epitopes.
目的建立、改进并完善从细菌表面展示随机肽库中进行抗原表位筛选及鉴定的方法。
To establish an improved procedure for isolation and identification of epitopes from a random peptide library displayed on the bacterial surface.
单抗与病毒之间的反应差异性表明HN蛋白上的部分抗原表位存在着较明显的变异。
The different reactive profile of the MAbs with the NDV strains demonstrated the presence of antigenic variation on the HN protein.
如果大肠杆菌中表达的VP1和VP2融合蛋白也能形成中和抗原表位,则解决了这个问题。
If the fusion protein of VP1 and VP2 that was expressed in E. coli can form neutralizing antigen epitopes, this problem is resolved.
结论:在外源抗原表位表达系统中表达的HBV重组抗原表位具有良好的抗原性,有诊断应用价值。
Conclusion HBV epitope expressed in a foreign epitope-presenting carrier possessed good antigenicity and diagnostic value.
在无HLAA2表型的感染者中,其感染后5年病毒抗原表位肽段既无共有序列的变异,也无琥珀突变。
However, in the HLA A2 - individual, the epitope had neither variation nor amber mutation in 5 years after infection.
结论已成功构建了人hsp70与MAGE - 4抗原表位基因的原核表达载体,为疫苗研究提供了依据。
Conclusion the prokaryotic expression vector for HSP70 and MAGE-4 epitope genes was successfully constructed, which provided a basis for the development of vaccine.
在线用蛋白质二级结构预测软件分析MAGE - 4抗原表位,PCR获取MAGE - 4抗原特征表位基因。
Analyze MAGE-4 antigen epitope by online predict software of protein secondary structure and amplify the epitope gene by PCR.
结果:设计并合成了SARS冠状病毒S蛋白的抗原表位序列的新基因序列,在大肠杆菌中实现了该基因的高表达。
Results: The new gene encoding the antigen epitope of SARS-CoV S protein was designed and synthesized successfully, and it was highly expressed in E coli.
结论制备了具有高亲和性和特异性的3d聚合酶多克隆抗体,为3d聚合酶的生物学功能和抗原表位研究奠定了基础。
This polyclonal antibody may lay a foundation for the further studies on the biological functions and epitopes of the 3d polymerase of FMDV.
目的构建表达P30蛋白抗原表位的重组质粒及工程菌,获得纯化的P30蛋白抗原表位,用于检测弓形虫特异性抗体。
Objective To construct a recombinant plasmid containing P30 gene of Toxoplasma gondii and obtain recombinant protein Methods P30 gene fragment was amplified from genomic DNA of T.
抗原表位是研究抗原的免疫机制和表位疫苗的基础,近年来在表位研究方面取得了一些可喜的进展,特别是抗原表位的研究方法。
Antigen epitopes lay the foundation for studying the immunity mechanism and epitope vaccine. A tremendous advancement of epitope was made, particularly of methodology.
整个筛选过程中抗原与抗体的结合在液相中完成,不仅消除了固相介质对抗原表位的影响,也更有利于噬菌体抗体与抗原的充分作用。
The binding process of antigen and antibody completed in the solution, which doesn't have the shortage of conformational changes encountered in the immobilized screening.
本课题基于可重复使用的免疫磁珠技术,抗原表位分析预测技术,多肽合成及筛选技术,建立了一种简捷快速高效的特异抗体检测方法。
The method is based on the the immunomagnetic beads that can be used repeatedly, the technology of investigating epitopes and the technology of synthesizing multiple antigen peptides.
本课题基于可重复使用的免疫磁珠技术,抗原表位分析预测技术,多肽合成及筛选技术,建立了一种简捷快速高效的特异抗体检测方法。
The method is based on the the immunomagnetic beads that can be used repeatedly, the technology of investigating epitopes and the technology of synthesizing multiple antigen peptides.
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